Multiple sclerosis research articles. Top 10 Multiple Sclerosis Stories of 2022 2022-10-20
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Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system (CNS), including the brain, spinal cord, and optic nerves. It is characterized by the immune system attacking and damaging the protective myelin sheath that surrounds nerve fibers, leading to symptoms such as muscle weakness, numbness, and vision problems. The course of the disease is highly variable, with some people experiencing mild symptoms while others may have severe and progressive disability.
There has been significant progress in the research and understanding of MS in recent years, and numerous articles have been published on the topic. Here are some key points that have emerged from recent research on MS:
The cause of MS is not fully understood, but it is thought to involve a combination of genetic and environmental factors. Research has identified a number of genetic risk factors for MS, and there is evidence that certain infections and environmental exposures may increase the risk of developing the disease.
There is no cure for MS, but a number of treatments are available that can slow the progression of the disease and reduce symptoms. These treatments include medications that modify the immune system (e.g., interferons, glatiramer acetate) and those that target specific symptoms (e.g., muscle relaxants, antidepressants).
Research has shown that early and aggressive treatment of MS can improve outcomes and reduce the risk of disability. This has led to the development of new treatment guidelines that recommend starting treatment as soon as possible after diagnosis.
Rehabilitation plays an important role in managing the symptoms of MS and improving quality of life. Physical therapy, occupational therapy, and speech therapy can all be helpful in addressing specific symptoms and helping people with MS maintain their independence.
Emerging research is investigating the potential use of stem cells and other regenerative therapies for the treatment of MS. While these approaches are still in the early stages of development, they hold promise for potentially repairing damaged nerve tissue and improving outcomes for people with MS.
Overall, the research on MS continues to advance our understanding of this complex disease and is leading to the development of new and more effective treatments. While there is still much to learn, the hope is that these advances will ultimately lead to a cure for MS and improve the lives of the millions of people affected by this disease.
Top 10 Multiple Sclerosis Stories of 2022
This can lead to an array of different symptoms, as Antje was describing. A recent Pedobacteria, Flavobacterium, Pseudomonas, Mycoplana, Acinetobacter, Eggerthella, Dorea, Blautia, Streptococcus, and Akkermansia bacteria in their intestines than people without MS. I was incredibly fatigued. They identified an antibody present in approximately 20-25% of MS patients that cross-reacted with both the EBV antigen and CNS protein. Axons speed transmission of impulses among nerve cells in the brain and spinal cord. During remissions, many people with MS feel close to normal.
However, people with MS had as many stimulating neurons as those without the condition. Among the MS patients, lower cholesterol levels in the CSF might correlate with a more severe disease course, the researchers noted. Feelings of overwhelming exhaustion are common in people with multiple sclerosis. Most of these patients use cannabis products daily, and the vast majority said these products were helpful for managing MS symptoms such as sleep problems, pain, and No. Siponimod harnesses specific white blood cells that attack myelin and prevents them from circulating in the body. And then, we also did an additional analysis looking at who amongst them was negative for EBV at the start of the military duty period, and there were only 35.
Multiple sclerosis: The most recent research on treatments
Methylprednisone Solu-Medrol, Depo-Medrol , given through a vein, is usually the first choice for severe attacks. So it seems like EBV really makes your risk of developing the disease jump up, but then there are other factors needed that further modify your risk. So I was going to carry on working at least a bit. So really, the main thing is to find the underlying mechanisms. . We wanted to find a group of individuals who were not infected by EBV and follow them over time. What brings them on? A clinical trial called Results showed that patients who intermittently fasted had lower levels of certain inflammatory T-cells that contribute to the development and progression of MS.
Multiple Sclerosis articles: The New England Journal of Medicine
This is why we think it is the leading cause of MS because nothing no other risk factor ever looked at comes even close to that. Hilary Guite: Antje, how did you know you had MS? Compared with control subjects without MS, these patients had significantly lower cholesterol levels in their blood and in the fluid around the brain and spinal cord, known as cerebrospinal fluid or CSF. Asked about how the study might help the future of MS treatment, Prof. Build a support network. With the introduction of COVID-19 vaccines, scientists have investigated whether people with MS who take medications such as cladribine can have adequate responses to vaccines.
What these drugs do is minimize the B cells available circulating in the blood. About half of people with relapsing-remitting multiple sclerosis eventually enter a secondary phase. The attack causes lesions to form, and over time, these cause scarring, which leads to nerve damage and reduced function. In previous studies, we and other research teams compared MS patients to healthy individuals and observed certain features more common in the immune systems of MS patients, but our twin study showed these differences in immune signatures are driven primarily by the genetics. Treating MS Scientists do not fully understand the risk factors for MS and the mechanisms of the condition.
Multiple sclerosis: Recent research on causes and treatments
Multiple sclerosis makes people tired. They decrease the action of immune cells that may cause nerve damage. We have added reference links to key research findings mentioned in the podcast. Share on Pinterest Design by Diego Sabogal. Guite: You had a Dr.
And in this cohort, we identified those who developed MS during their military service through medical record reviews. It depends on gender, so women are more likely to develop MS. So if we were to have more targeted treatments, for example, antivirals, then maybe we could better treat MS, if EBV is involved. The first neurologist — all my examinations by him were actually normal. Disease-modifying medications help slow the speed at which multiple sclerosis gets worse. The latest This result gives scientists and others in the medical community hope that people who take these drugs for MS will have similarly adequate responses to COVID-19 vaccines. In this feature, we look at some of the key studies of the past year and present some expert perspectives on the impact of this research.
I worked far too long, for too many hours, and put it down to that. Maybe it was the Dr. And then, they went on to develop MS. It can help improve your strength, balance, coordination, and overall health and well-being. I mean, that was my main issue recently. So what does this tell us about treatment for MS? Because you can imagine if people get infected early in life, mainly with EBV, then such a vaccine would need to be given early in life and also convey sterile immunity throughout life.
