P aminobenzoic acid ir. PARA 2022-10-06

P aminobenzoic acid ir Rating: 8,5/10 1489 reviews

p-Aminobenzoic acid (p-aminobenzoate or p-aminobenzoate) is an organic compound that is widely used in the synthesis of a variety of chemicals and compounds, including dyes, pharmaceuticals, and cosmetics. It is a white, crystalline solid that is soluble in water and has a melting point of about 300°C.

p-Aminobenzoic acid is a derivative of benzoic acid, which is a common constituent of many plant and animal tissues. It is synthesized by the hydrolysis of p-aminobenzoic acid esters, which are formed from the reaction of benzoic acid with primary amines.

One of the most important uses of p-aminobenzoic acid is in the synthesis of sulfonamides, which are a class of antibiotics that are used to treat bacterial infections. p-Aminobenzoic acid is also used in the synthesis of a variety of other pharmaceuticals, such as vitamin B6 and folic acid.

In addition to its use in the synthesis of pharmaceuticals, p-aminobenzoic acid is also used in the synthesis of dyes and pigments, as well as in the production of resins, plastics, and rubber. It is also used as a food additive, as it can help to preserve the color and flavor of certain foods.

p-Aminobenzoic acid is generally considered to be a safe and effective compound, although it can cause allergic reactions in some individuals. It is classified as a category C pregnancy drug, which means that it may be harmful to a developing fetus if it is taken during pregnancy.

In conclusion, p-aminobenzoic acid is a versatile compound that has a wide range of uses in the synthesis of pharmaceuticals, dyes, pigments, and other chemicals. It is generally considered to be safe and effective, although it can cause allergic reactions in some individuals and should be used with caution during pregnancy.

PARA

p aminobenzoic acid ir

Taking PABA by mouth and getting a cortisone shot might increase the effects and side effects of cortisone. Additionally, there are a smaller set of peaks between the 3000-3500 cm-1 range on the IR spectrum analysis of both materials. Modification of local anesthetic toxicity by vasoconstrictors. Covington TR, et al. Treatment of peyronie's disease with para-aminobenzoacidic potassium POTOBA.

Next

The Synthesis of Benzocaine, a Common Anesthetic

p aminobenzoic acid ir

Liver toxicity from potassium para-aminobenzoate. Ultraviolet light induction of peripheral granulocytosis with splenomegaly: protection of mice with topical p-aminobenzoic acid PABA. Pereira de Godoy, J. All accesses are recorded. J Am Acad Dermatol 1983;9:770. Our product percent yield for benzocaine is 17%. Sunscreens: Topical and systemic approaches for protection of human skin against harmful effects of solar radiation.

Next

SDBS

p aminobenzoic acid ir

It is prohibited that you use any information of SDBS for profit-making or commercial use without obtaining proper permission from us. This could have been caused by a number or lurking variables or simply from human error. However, from this melting point range, we can infer that our product was almost completely pure. Topical protection against long-wave ultraviolet A. If more spectra are required for some specific purpose or commercial use, you should consult us and describe the intended usage or purpose of our SDBS.

Next

p aminobenzoic acid ir

When applied into the eye: PABA is POSSIBLY SAFE when a solution is used as an eye drop in the eyes. Retrospective studies in scleroderma: pulmonary findings and effect of potassium p-aminobenzoate on vital capacity. Peyronie's disease: review of nonsurgical treatment options. After this we added 1. PABA can cause skin irritation and might also stain clothing with a yellow color. After this we added 1 mL of H2SO4.

Next

p aminobenzoic acid ir

Biotransformation of para-aminobenzoic acid and salicylic acid by PMN. Treatment of lichen sclerosus with potassium para-aminobenzoate. Darkening of gray hair during para-amino-benzoic acid therapy. Potassium paraaminobenzoate POTABA in the treatment of Peyronie's disease: a prospective, placebo-controlled, randomized study. Washington, DC: American Pharmaceutical Association, 1996. More evidence is needed to rate the effectiveness of PABA for these uses. Eur J Clin Nutr 2003;57:138-42.

Next

p aminobenzoic acid ir

This is a considerably low percent yield. Once this was done we used gravity filtration and rotary evaporation to collect 0. Anesthesiology 1995;82 6 :1463-1473. Conclusion: In conclusion, this experiment was partly successful. After this we added 26 mL of Na2CO3 slowly, one mL at a time dropwise, to get a pH of 9.

Next

p aminobenzoic acid ir

Effects of potassium para-aminobenzoate on growth and macromolecule synthesis in fibroblasts cultured from normal and sclerodermatous human skin, and rheumatoid synovial cells. The synergistic action of para-aminobenzoic acid and cortisone in the treatment of rheumatoid arthritis. Preliminary assessment of glycine conjugation of para-aminobenzoic acid as a quantitative test of liver function. Our experimental melting point was very similar to the actual melting point of the product. Br J Dermatol 1991;125 3 :222-226. J Androl 2009;30 4 :397-405.

Next

p aminobenzoic acid ir

An in vitro and in vivo study. The actual melting point of Benzocaine us 92 degrees celsius and the melting point of p-aminobenzoic acid is 157-189 degrees celsius. We did not obtain an exact melting point. Dermatol 1983;9 3 :354-360. The known melting point for benzocaine is 92 degrees celsius.

Next

p aminobenzoic acid ir

Dis 1986;68 1 :29-34. Conclusion: In conclusion, this experiment was partly successful. Taking more than 12 grams per day can cause serious side effects such as liver, kidney, and blood problems. Pharmacological Management of Peyronie's Disease. The actual melting point of Benzocaine us 92 degrees celsius and the melting point of p-aminobenzoic acid is 157-189 degrees celsius. Wiesel LL, Barritt AS, Stumpe WM. We did not obtain an exact melting point.

Next

p aminobenzoic acid ir

Para-aminobenzoic acid PABA might decrease how quickly the body breaks down cortisone. Medical management of Peyronie's disease. Drug Facts and Comparisons. Clegg DO, Reading JC, Mayes MD, et al. Influence of gastric emptying on the PABA test. The Synthesis of Benzocaine, a Common Anesthetic Purpose: The purpose of this experiment is to synthesize benzocaine from p-aminobenzoic acid using an esterification reaction.

Next